摘要
发热伴血小板减少综合征(severe fever with thrombocytopenia syndrome, SFTS)是一种新发的蜱媒传染病。SFTS主要在东亚地区流行,疾病高发期为每年的夏秋两季,该病主要通过蜱叮咬传播,由大别班达病毒(Dabie bandavirus, DBV)引起,主要症状包括发热、血小板和白细胞减少,严重可致多器官功能衰竭。目前我国将SFTS按照乙类传染病管控。DBV基因组由小(S)、中(M)、大(L) 3个RNA片段组成,且不同基因型致病情况不同。为更详细地了解SFTS,本文从病原学、发病机制、流行情况、传播途径及遗传多样性等方面对近年来的研究进行综述。
Severe fever with thrombocytopenia syndrome(SFTS)is a new tick-borne disease.SFTS is mainly prevalent in East Asia,with a high incidence in the summer and autumn of each year.The disease is mainly transmitted by tick bites.SFTS is caused by Dabie bandavirus(DBV),and the main symptoms include fever,thrombocytopenia and leukopenia,even severe multiple organ failure.The disease is currently under the control of Class B infectious diseases in China.The genome of DBV consists of three RNA fragments:small(S),medium(M),and large(L).Pathogenicity differs by genotype.To better understand SFTS,this paper summarizes recent studies from the aspects of aetology,pathogenesis,prevalence,route of transmission and genetic diversity.
作者
贾佳
韦雨露
曹淦
甄茜
田诚
潘杰
陈安喜
王泽敏
吕旭峰
JIA Jia;WEI Yulu;CAO Gan;ZHEN Qian;TIAN Cheng;PAN Jie;CHEN Anxi;WANG Zemin;LYU Xufeng(School of Public Health,Nanjing Medical lniversity,Nanjing,Jiangsu 211103,China;Changzhou Advanced Institute of Public Health,Nanjing Medical University,Changzhou,Jiangsu 213022,China;School of Economics and Management,Nanjing University of Chinese Medicine,Nanjing,Jiangsu 210023,China;Changzhou Center for Disease Control and Prevention,Changzhou,Jiangsu 213022,China)
出处
《中华卫生杀虫药械》
2025年第4期464-471,共8页
Chinese Journal of Hygienic Insecticides and Equipments
基金
2023年度江苏省预防医学科研课题项目(Ym2023013)。
