摘要
目的:观察加味补阳还五汤联合通督调神针刺治疗脊髓损伤(SCI)后神经源性膀胱(NB)的临床疗效。方法:选取60例SCI后NB患者作为研究对象,按随机数字表法分为观察组及对照组各30例。对照组给予现代医学常规治疗,观察组在对照组基础上给予加味补阳还五汤联合通督调神针刺治疗。2组均以4周为1个疗程,共治疗2个疗程。比较2组临床疗效,比较2组治疗前后尿流动力学指标及排尿功能相关水平的变化,观察2组治疗期间不良反应发生情况。结果:观察组临床疗效总有效率为90.00%,对照组为66.67%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组最大膀胱容量、最大尿流率指标值均较治疗前上升,残余尿量均较治疗前下降,差异均有统计学意义(P<0.05);治疗后,观察组最大膀胱容量、最大尿流率指标值均高于对照组,残余尿量低于对照组,差异均有统计学意义(P<0.05)。治疗后,2组24 h排尿次数、尿失禁次数均较治疗前减少,单次排尿量均较治疗前增加,差异均有统计学意义(P<0.05);治疗后,观察组24 h排尿次数、尿失禁次数均少于对照组,单次排尿量大于对照组,差异均有统计学意义(P<0.05)。治疗期间,2组均未发生严重不良反应。结论:加味补阳还五汤联合通督调神针刺应用于SCI后NB的治疗中,可提高临床疗效,改善患者的排尿情况和尿流动力学指标。
Objective:To observe the clinical effect of the therapy of modified Buyang Huanwu tang combined with Tongdu Tiaoshen acupuncture on neurogenic bladder(NB)after spinal cord injury(SCI).Methods:A total of 60 patients with NB after SCI were selected and divided into the observation group and the control group according to the random number table method,with 30 cases in each group.The control group was given routine treatment in modern medicine,and the observation group was additionally treated with modified Buyang Huanwu tang combined with Tongdu Tiaoshen acupuncture based on the treatment of the control group.Both groups were treated for two courses,four weeks being a course.The clinical effects were compared between the two groups.Before and after treatment,the changes of urodynamic indexes and related levels of urinary function were compared between the two groups.During treatment,the incidence of adverse reactions in the two groups was observed.Results:The total clinical effective rate was 90.00%in the observation group,and was 66.67%in the control group,the difference being significant(P<0.05).After treatment,the values of maximum bladder capacity and maximum urinary flow rate in the two groups were increased when compared with those before treatment,and the residual urine volume was decreased,differences being significant(P<0.05);after treatment,the values of maximum bladder capacity and maximum urinary flow rate in the observation group were higher than those in the control group,and the residual urine volume in the observation group was lower than that in the control group,differences being significant(P<0.05).After treatment,the times of 24-hour urination and urinary incontinence in the two groups were decreased when compared with those before treatment,and the single urination volume was increased,differences being significant(P<0.05);after treatment,the times of 24-hour urination and urinary incontinence in the observation group were less than those in the control group,and the single urination volume was greater than that in the control group,differences being significant(P<0.05).During treatment,no serious adverse reactions occurred in both groups.Conclusion:The therapy of modified Buyang Huanwu tang combined with Tongdu Tiaoshen acupuncture for NB after SCI can enhance the clinical effect and improve the urination and urodynamic indexes of patients.
作者
詹玉华
刘晓广
孙盛杰
涂七妹
ZHAN Yuhua;LIU Xiaoguang;SUN Shengjie;TU Qimei
出处
《新中医》
CAS
2022年第15期36-40,共5页
New Chinese Medicine
基金
宁波市鄞州区科技局课题(2020AS0083)。
关键词
脊髓损伤
神经源性膀胱
补阳还五汤
通督调神针刺
Spinal cord injury
Neurogenic bladder
Buyang Huanwu tang
Tongdu Tiaoshen acupuncture
