摘要
高血压是老年人常见的慢性疾病,发病率逐年上升,我国高血压患者多为H型高血压,研究表明H型高血压与认知功能障碍相关。高血压和高同型半胱氨酸是心脑血管病的独立危险因素,且高同型半胱氨酸血症可能通过神经毒性、内皮损伤等方面进而导致认知功能明显减低。目前没有针对神经退行性疾病预防和治疗的有效策略,因此探索认知功能潜在危险因素、明确H型高血压与认知功能关系至关重要。文章对老年人H型高血压与认知功能障碍的关系研究进展作一综述。
Hypertension is a common chronic disease in the elderly.The incidence of hypertension is increasing year by year.Most of the hypertensive patients in China are type H hypertension.Studies have shown that type H hypertension is related to cognitive impairment.Hypertension and homocysteine are independent risk factors of cardiovascular and cerebrovas -cular diseases,and hyperhomocysteinemia may decrease the cognitive function through neurotoxicity, endothelial damage and so on.There is no effective strategy for the prevention and treatment of neurodegenerative diseases.Therefore,it is important to explore the potential risk factors of cognitive function and to identify the relationship between type H hypertension and cogni -tive function.
出处
《疑难病杂志》
CAS
2017年第12期1283-1287,共5页
Chinese Journal of Difficult and Complicated Cases
基金
教育部人文社科规划基金项目(16YJAZH034)
北京市卫计委保健科研课题(京17-12)
