摘要
背景:随着老龄化社会的到来,认知功能障碍发病率的逐渐上升,人们开始关注吸烟对认知功能障碍的影响。目的:探讨吸烟对老年人认知功能障碍的影响,寻求进行干预的可能性。设计:随机整群抽样调查。单位:一所大学医院的神经内科。对象:以抽签的方法从重庆市高新区、渝北区、渝中区中分别抽取了两个居委会≥60岁老年人共3012人,男1668人,女1344人。方法:用简易智能量表(MMSE)进行认知功能测定,采用t检验和Lo-gistic回归多因素分析方法对测定结果进行分析。主要观察指标:①吸烟的人口学分布。②老年人认知功能障碍的单因素和多因素分析结果。结果:对3012人完成了MMSE测定,总吸烟率为35%,重庆市老年人认知功能异常率为11.95%;吸烟人群中,现在吸烟者引起认知功能障碍为11.8%,过去吸烟者为4.5%,不吸烟者引起认知功能障碍为5.3%。结论:吸烟与认知功能障碍密切相关(χ2=6.59,P=0.047),文化程度、年龄、职业和性别均是老年人认知功能障碍的影响因素。吸烟人群中现在吸烟者对认知功能障碍的危险性较大(RR=2.33,95%CI=1.37～5.82)。吸烟是老年人认知功能减退的重要危险因素,老年人戒烟可能是降低认知功能障碍发生的有效策略。
BACKGROUND:With the trend of population aging,the morbidity of cognitive dysfunction has been gradually increased.People start to pay attention to the impact of smoking to cognitive dysfunction.OBJECTIVE:To investigate the effects of smoking on cognitive dysfunction in elder people,and explore the possibility of intervention.DESIGN:Randomized cluster sampling. SETTING:Neurology Department of a hospital. PARTICIPANTS:A total of 3 012 old people aged above 60 year were selected from two resident committees by drawing from Gaoxin district,Yubei district and Yuzhong district of Chongqing in which there were 1 668 males and 1 344 females.METHODS:Mini mental state examinate(MMSE) was used to assess cognitive function.t test and Logisitc regression were used to analyze the information.MAIN OUTCOME MEASURES:①Demographic distribution of smoking.②Single factor and multiple factors analysis of cognitive dysfunction in aged people.RESULTS:MMSE assessment was conducted to 3 012 people,the total smoking rate was 35%.The abnormality rate of cognitive function in aged people of Chongqing was 11.95%.Among smoking population,11.8%of the currently smoking people and 4.5%of previously smoking people suffered from the cognitive dysfunction while 5.3%of the non smoking people got cognitive dysfunction.CONCLUSION:Smoking is closely correlated with cognitive dysfunction(χ2=6.59,P=0.047) and education background, age, occupation and sex are the influencing factors of cognitive dysfunction.Current smoking people get higher risk to suffer cognitive dysfunction(RR=2.33,95%CI=1.37-5.82).Smoking is an important risk factor for cognitive dysfunction in aged people so that it will be an effective strategy for aged people to reduce the incidence of cognitive dysfunction by quitting smoking.
出处
《中国临床康复》
CSCD
北大核心
2005年第4期228-230,共3页
Chinese Journal of Clinical Rehabilitation
