摘要
目的研究中文版蒙特利尔认知评估量表(MoCA)在遗忘型轻度认知障碍(aMCI)诊断筛查中的作用。方法以2009-05-2010-03在卫生部北京医院神经内科门诊就诊的患者为检查对象,筛选出aMCI患者31例及健康对照者30名,分别进行简易精神状态量表(MMSE)、MoCA等量表检测,计算两量表诊断aMCI的敏感性和特异性并进行比较,分析MoCA在诊断aMCI中的作用和特点。结果以26分作为分界值时,MMSE和MoCA诊断aMCI的敏感性分别为9.68%和87.10%,特异性分别为93.33%和73.33%。MoCA的敏感性显著高于MMSE。结论与MMSE相比,MoCA以其较高的敏感性在筛查aMCI中具有较大作用,而且可对多个认知领域的功能进行检测,有望在多个认知损害类型的研究中起到重要作用。
Objective To study the effect of Motreal cognitive assessment（MoCA）（Chinese version） in diagnosing the amnestic mild cognitive impairment.Methods A total of 61 persons were chosen from the outpatient section of Beijing Hospital（2009-05-2010-03）,including 31 patients who meeting the criteria of MCI-Revised（MCI-R） and 30 normal controls（NC） for comparing the sensitivity and specificity of the mini-mental state examination（MMSE） and MoCA in diagnosing the aMCI and analysing the effect and characteristics of MoCA in diagnosing the aMCI.Results When using the cut off score of 26,the sensitivity of MMSE and MoCA are 9.68% and 87.10% separately,the specificity are 93.33% and 73.33%.Conclusions MoCA might play an important role in screening aMCI and the other cognitive impairments due to the better sensitivity of MoCA and its wide cover of multiple cognitive district.
出处
《中国神经免疫学和神经病学杂志》
CAS
2011年第2期91-93,97,共4页
Chinese Journal of Neuroimmunology and Neurology
