摘要
笔者先概括性介绍目前临床常用氨基糖苷类抗生素的来源、分类、化学结构、组分多样性及原研单位等基本信息,然后回顾氨基糖苷类抗生素组分分析技术发展历程,通过对比分析,讨论常见氨基糖苷类抗生素组分分析方法的优缺点,分析液相色谱脉冲安培电化学检测方法在氨基糖苷类抗生素组分分析应用中优势,最后介绍与氨基糖苷类抗生素组分分析相关的新技术和新理念,探讨其未来的发展方向。
This paper first briefly introduces the basic information of aminoglycosides for pharmaceutical use such as origin,classification,chemical structures,diversity of composition and the research originators,etc.Then it reviews the development process of the technologies for the analysis of components of aminoglycosides,discusses the advantages and disadvantages of current methodologies and explains the advantage of liquid chromatography coupled with pulsed amperometric detection method for analysis of the components of aminoglycosides.At last,it introduces some new analysis technologies and ideas and forecasts the direction of future development.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2017年第20期1772-1779,共8页
Chinese Pharmaceutical Journal