摘要
以芳香醛、2-氨基吡啶和异腈为原料,10 mol%分子碘作催化剂,甲醇作溶剂,回流反应3 h合成标题化合物。该反应条件温和,产率为76%~90%,相应的结构经过红外、核磁共振和质谱表征确认。
3-Aminoimidazo[1,2-a]pyridine derivatives have been synthesized via one-pot method with aromatic aldehyde,2-aminopyridine and isocyanide,using methanol as solvent,10 mol% iodine as catalyst in relux. The reaction condition is mild,and the corresponding yields are among 76% - 90%.The products were characterized by IR,NMR and HRMS.
出处
《化学试剂》
北大核心
2017年第9期1011-1014,共4页
Chemical Reagents
基金
2017年常州工程职业技术学院"绿色催化与应用酶"院级科研团队经费资助项目(111308002216006)
