摘要
根据Biziagos与Passagot所报告的实验数据,通过回归方程与消失速率常数的计算,表明不论在自净或戊二醛作用下,HAV感染性的消失均较其抗原性为快。
In order to determine whether it is appropriate to use disappearance of antigenicity as the indicator of loss of infectivity in HAV disinfection test, a statistical analysis was carried out. In the study the data reported by Biziagos and Passagot were compared by regression equation of action time (t) and logarithm of preserving rate (logN_t/N_0) and also by calculation of speed constant (K) of loss. The result indicated that the speed constant of loss of infectivity was significantly different from that of disappearance of antigenicity. In mineral water, the speed constant of natural loss of HAV infectivity was 2.42(4℃) to 3.25 (23℃) times higher than that of disappearance of antigenicity. Under the action of glutaraldehyde, the speed constant of loss of infectivity was 4.9～5.2 times (the concentration of glutaraldehyde was 0.02%～0.50%) higher than that of disappearance of antigenicity. According to the above calculation results, it is indicated that under experimental condition, the infectivity of HAV loses more rapidly than antigenicity.
出处
《中国消毒学杂志》
CAS
北大核心
1991年第3期138-142,共5页
Chinese Journal of Disinfection
关键词
甲肝病毒
抗原性
感染性
Hepatitis A virus antigenicity infectivity constant of loss rate
