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CD4^+CD25^+调节性T细胞在病毒感染性疾病中的作用 被引量：4

The role of CD4^+ CD25^+ and regulating T-cell in viral diseases
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摘要 CD4^+ CD25^+调节性T细胞(CD4^+ CD25^+ Treg)是近年来确定的一类具有免疫抑制功能的T细胞亚群,主要通过细胞与细胞间直接接触和分泌抑制性细胞因子发挥作用,在维持机体免疫自稳、防止自身免疫以及抗感染免疫、肿瘤免疫、移植免疫、变态反应等方面起着重要作用。新近研究发现,CD4^+ CD25^+ Treg数量和功能异常与病毒感染性疾病的发生、发展关系密切。本文就CD4^+ CD25^+ Treg作用机制及其在病毒感染性疾病中的作用进行综述。
作者 卢创林 钱起丰
机构地区 深圳市皮肤病防治研究所 广东医学院皮肤性病研究所
出处 《中国热带医学》 CAS 2007年第1期115-117,共3页 China Tropical Medicine
关键词 T淋巴细胞 调节性 FOXP3 抑制性膜分子 细胞因子 感染 病毒
分类号 R392.12 [医药卫生—免疫学]
  • 相关文献

参考文献27

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共引文献24

同被引文献49

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引证文献4

二级引证文献34

中国热带医学
2007年 第1期

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