摘要
目的:观察自拟补肾活血方治疗冠状动脉粥样硬化性心脏病(简称冠心病)PCI术后心绞痛的临床疗效。方法:选取2014年2月—2015年3月本院心血管科收治的冠心病PCI术后再发心绞痛的住院患者82例,随机分为治疗组和对照组,每组41例。对照组给予常规抗心绞痛药物治疗,治疗组在对照组治疗的基础上加用自拟补肾活血方治疗。结果:治疗组有效率95.1%,对照组有效率70.7%,治疗组优于对照组(P<0.05);两组患者治疗后临床中医证候积分均较治疗前下降,差异均有统计学意义(P<0.05),对照组治疗后中医证候积分为(13.34±7.28)分,治疗组治疗后中医证候积分为(19.81±7.25)分,治疗组优于对照组(P<0.05);两组患者治疗后24h缺血发作次数、缺血总时间、缺血最长持续时间、室性早搏次数均明显降低,与治疗前比较差异有统计学意义(P<0.05),且治疗组上述四项指标改善情况优于对照组(P<0.05)。结论:自拟补肾活血方治疗冠心病PCI术后心绞痛临床疗效确切。
Objective： To observe the clinical effects of Kidney-Tonifying and Blood-Activating Formula on angina of patients after PCI operation of coronary heart disease（ CHD）. Methods： Totally 82 cases with angina after PCI operation of CHD hospitalized between February 2014 and March 2015 were randomly divided into treatment group and control group,with 41 cases in each group. Control group were given conventional anti-angina drugs while treatment group were additionally given Kidney-Tonifying and Blood-Activating Formula for the treatment. Results： The effective rate was 95. 1% in treatment group and 70. 7% in control group,with statistical significance（ P 〈 0. 05）. The scores of clinical TCM symptoms in both groups got declined after the treatment; the difference had statistical significance（ P 〈 0. 05）. The score of linical TCM symptoms was（ 19. 81 ± 7. 25） in treatment group and（ 13. 34 ± 7. 28） in control group（ P 〈 0. 05）. After 24 h,the occurrence times of ischemia,duration of ischemia,the longest duration of ischemia,and times of ventricular premature beat in both group obviously declined; the difference had had statistical significance compared with these before the treatment. The improvements of the above four indicators in treatment group were better than these in control group. Conclusion： Kidney-Tonifying and Blood-Activating Formula has definite clinical therapeutic effects on angina of patients after PCI operation of CHD.
出处
《河南中医》
2016年第3期447-449,共3页
Henan Traditional Chinese Medicine
基金
河南省科技厅科技攻关课题(编号:132102310223)
