摘要
目的:观察瑞舒伐他汀和替米沙坦对原发性高血压(EH)并发阵发性心房纤颤(AF)患者心电图P波时限和离散度及AF发生率的影响。方法:EH并发阵发性AF患者56例,随机分为2组:替米沙坦(80 mg/d)加瑞舒伐他汀(10 mg/d)组(联合用药组)和替米沙坦(80 mg/d)组。共观察6个月。分别于用药前后测定12导联体表心电图中P波的时限和P波离散度及AF发生率。结果:用药后两组均可使EH并发阵发性EH患者心电图P波的时限和P波离散度减小,组间比较显示,联合用药组的作用优于单用替米沙坦组。结论:瑞舒伐他汀合用替米沙坦对EH并发阵发性AF患者窦律的维持及预防AF发生的作用优于单用替米沙坦。
AIM：To study the effects of rosuvastatin and telmisartan on P-wave dispersion in eletrocardiography in patients with essential hypertension（EH）.METHODS：Fifty-six patients were randomly divided into telmisartan（80 mg/day） plus rosuvastatin（10 mg/day） group and telmisartan（80 mg/day） group and were monitored for 6 months.P-wave duration and P-wave dispersion were detected before and after using the drugs.RESULTS：After using the drugs,P-wave duration and P-wave dispersion in both groups of patients with EH decreased（P0.05）.Compared with telmisartan alone,rosuvastatin plus telmisartan had more obvious effect on P-wave dispersion.CONCLUSION：Treatment with rosuvastatin and telmisartan has more effective value in preventing atrial fibrillation than using telmisartan only in patients with EH.
出处
《心脏杂志》
CAS
2012年第1期54-56,共3页
Chinese Heart Journal
