摘要
目的探讨儿童腺样体肥大的临床药物治疗后的效果分析。方法选取2014年3月至2015年4月因患有腺样体肥大于耳鼻喉门诊就诊并治疗的患儿80例,按照随机分配的原则,40例采用糠酸莫米松鼻喷剂进行治疗的患儿为对照组,另40例在对照组患儿用药的基础上联合孟鲁司特钠颗粒进行治疗的患儿为观察组,比较两组患儿的临床治疗效果。结果在针对两组患儿治疗后呼吸相关睡眠障碍指标的比较中,对照组和观察组患儿在治疗后的症状评分分别为(3.3±1.1)、(0.7±0.6)分;咳嗽时间分别为(55.7±10.5)、(20.0±11.1)d;A/N比值分别为0.8±0.1和0.6±0.1,观察组患儿在治疗后3项指标的改善程度均明显优于对照组患儿,且差异有统计学意义(P<0.01)。结论在对腺样体肥大患儿进行治疗的过程中采用糖皮质激素联合白三烯受体拮抗剂治疗可有效缓解临床症状,消除不良体征,值得临床上推广使用。
Objective To analyze the clinical effect of medication treatment in children patients with adenoid hypertrophy.Methods 80 cases of child adenoid hypertrophy in the ear nose and throat outpatient department of our hospital from March 2014 to April 2015 were selected and grouped according to the random principle.The control group（40cases）was given the mometasone furoate nasal spray for treatment,while on this basis the observation group（40cases）was combined with Montelukast Granules for treatment.The clinical therapeutic effects were compared between the two groups.Results In the comparison of the breathing related sleep disorder indexes,the symptom scores after treatment in the control group and the observation group were（3.3±1.1）and（0.7±0.6）respectively;the cough time were（55.7±10.5）d and（20.0±11.1）d respectively;the A/N ratios were（0.8±0.1）and（0.6±0.1）respectively,the observation group was significantly better than the control group in the improvement of these 3indexes,and the differences were statistical significance（P〈0.01）.Conclusion Adopting corticosteroids combined with leukotriene receptor antagonist agent in treating adenoidal hypertrophy in children has the advantages of relieving clinical symptoms and eliminating adverse body signs,and is worthy of clinical promotion and use.
出处
《检验医学与临床》
CAS
2015年第22期3357-3358,3361,共3页
Laboratory Medicine and Clinic
关键词
儿童腺样体肥大
糠酸莫米松鼻喷剂
孟鲁司特钠
adenoidal hypertrophy
clinical diagnosis
mometasone furoate nasal spray
montelukast sodium
