摘要
本文报道了甲苯咪唑治疗14例肝泡状棘球蚴病患者的临床观察结果。近期和8年随访结果表明,甲苯咪唑对泡状棘球蚴病具有一定的治疗作用,结合外科手术可能提高治疗效果。因此进一步开展甲苯咪唑作用机理的研究对提高疗效是有重要意义的。
14 patients with echinococcus multilocularis were treated with mebendazole. The diagnosis of all the patients was confirmed by pathologic sections. Mebendazole was given in dosage of 1200mg a day to adult patient for 30 days as a course. Repetition of the treatment was after a interval of one week. During the treatment, the patients were well tolerated and the general condition improved. A follow up was made over 8 years for 12 nonoperative patients, 3 cases with clinical cure. 3 cases were worsened and 6 cases died in 1 to 3 years. It was shown that mebendazole has certain efficacy in echinococcus multilocalaris, combining with surgical operation, it is possible to stand a fairly scod chance of success in this disease.
基金
自治区卫生厅青年科研基金
关键词
棘球蚴病
甲苯咪唑
肝泡状
echinococcus multilocularis
alveolar hydatid disease
mebendazole
