摘要
目的 FISH是分析染色体畸变的有效方法 ,该方法的准确性受多种因素影响 ,用G显带方法验证FISH对早先X射线工作者染色体易位分析。方法 对X射线工作者同时采用两种方法分析染色体易位 ,进行统计学分析比较。结果 两种方法分析染色体易位率有很好相关性。结论 FISH方法是分析X射线工作者染色体易位率进行剂量重建的可行方法。
Objective FISH is the most effective way of detecting chromosome aberration and many factors affect its accuracy.G-banding is used to verify the results of early X-ray workers'chromosome translocation examined by FISH.Methods The chromosome translocations of early X-ray workers have been analysed by FISH(fluorescence in situ hybridization)and G-banding,yields of translocation treated with statistics.Results The chromosome aberrations frequencies by tow methods are closely related.Conclusion FISH is a feasible way to analyse chromosome aberrations of X-ray workers and reconstruct dose.
出处
《中国辐射卫生》
2002年第1期5-6,共2页
Chinese Journal of Radiological Health
