摘要
目的:研究正常人肺脏深呼、吸气末动态螺旋CT扫描的表现,初步确定其正常值范围。材料与方法:对55例健康成人进行呼、吸气末HRCT扫描及肺功能检查PFTs。以呼、吸气末肺野密度变化、象素指数PI值及面积变化率为CT评价指标。比较上述指标在左、右肺,上、中、下肺区及前、后肺区的变化规律,并比较全肺法和局部感兴趣区ROI法对肺野密度测量结果的相关性。结果:健康成人深呼、吸气末全肺平均CT值分别为-6815±386Hu和-8391±211HuP<001,其差值为1576±361Hu。呼、吸气末CT值左、右肺间无统计学差异P>01;上、中、下肺区吸气末平均CT值无差异P>005,呼气末CT值上肺区低于下肺区,呼、吸气末CT值差值下肺区最大,上肺区最小P<005。肺脏CT值分布呈前-后节段性差异,肺前部的呼、吸气末平均CT值及其差值变化均比肺后部低P<005,以呼气末更显著。深吸气末平均PI值为2962%12%～528%,深呼气末为065%0%～17%,两者有显著性差异P<0001。肺野面积变化率为384%,上肺区面积减少显著P<001。局部ROI法与全肺法测量的全肺平均CT值结果有显著相关性。结论:肺野密度、PI及面积变化率的测算是定量评估正常人肺脏动态CT表现及其功能很有价值的影像方法。
Objective:To quantify the findings in dynamic C T of healthy adults in full inspiration and full expiration scan-ning.Materials and Methods:Fifty-five healthy adults underwen t full respiratory CT scans and PFTs.The lung attenuation,pixel index(PI )and area reduction score were calcul ated.The above three parameters were studied among different lung levels.CT attenuation were calculated by the ROI method and the whole lung method .These two meth ods were compared.Results:The CT attenuation of lung in full expiration and inspiration were -681.5±38.6Hu and -839.1±21.1Hu (P<0.01)respectively.There was no signific ant difference between the right and the left lung(P>0.1).The CT attenuation became higher an d higher from the upper to the lower lu ng at end expiration(P>0.05).The gradient between the two respir atory phases of the lower lung was larger than that of the upper part(P<0.05).All the cases had mean PI 29.62%at in spiration with wider range of 1.2%～52.8%,and mean PI 0.65%at expiration with narrow range of 0%～2.7%(P<0.001).At the end of expiration phase,the c ross-sectional lung area of the grou p was 38.4%(P<0.01).The CT attenuation calculated by th e ROI method and the whole lung method showed high correlation.Conclusions:Measure-ments of lung CT attenuation,PI and r atio of area reduction are all valuab le methods of quantitative analysis in dynamic CT findings of lung.The ROI method is simple and easy to perform in clinical work.
出处
《中国临床医学影像杂志》
CAS
2001年第4期246-249,共4页
Journal of China Clinic Medical Imaging
