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原发性肝细胞癌的HLA-Ⅰ类抗原表达 被引量:1

Expression of HLA-Ⅰ Antigens in Primary Hepatocellular Carcinoma
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摘要 目的 确定体内原发性肝细胞癌细胞的 HL A - 类抗原表达情况。方法 采用免疫组织化学L SAB法对 6例原发性肝细胞癌冰冻组织进行研究。结果  6例标本的肝癌细胞都有较强的 HL A- 类抗原表达。结论 从 HL A- 类抗原表达角度看 ,研制肝癌 Objective To find out whether hepatocellular carcinoma (HCC) cells express HLA Ⅰantigens. Methods LSAB assay of immunohistochemistry was used to detect six frozen HCC specimens. Results All the HCC cells have strong expression of HLA I antigens. Conclusion In view of these data on the expression of HLA Ⅰantigens, the authors deem it practical to develop HCC CTL vaccine.
出处 《华西医科大学学报》 CAS CSCD 北大核心 2001年第4期495-496,504,共3页 Journal of West China University of Medical Sciences
基金 国家自然科学基金 (批准号 30 0 70 85 5 ) 华西医科大学基础青年基金资助 ( 0 36 )
关键词 原发性肝细胞癌 HLA-Ⅰ类抗原 免疫组织化学 Primary hepatocellular carcinoma HLA Ⅰantigens Immunohistochemistry
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