摘要
为探讨抗磷脂抗体 (a L Ps)与血管性痴呆 (VD)之间的关系 ,用固相酶联免疫吸附法 (EL ISA)检测了31例 VD患者 (VD组 )、42例脑梗死患者 (梗死组 )和 30例健康人 (对照组 )的血清抗心肌磷脂抗体 (a CL )。结果VD组、脑梗死组及对照组的阳性率分别为 2 7%、2 3%和 3% ,两患者组与对照组比较差异均有显著性 (P <0 .0 5 )。检查证实 a CL 阳性的 VD和脑梗死患者均无系统性红斑狼疮。 a CL 与 VD的发生有关 。
To study the relationship of antiphospho1ipid antibodies and vascular dementia(VD),ischemia cerebral vascular diseases(ICVD) Blood samples were obtained from 31 consecutive patients with vascular dementia,42 patients with cerebral infarction and 30 control Levels of aCL were measured by standardized ELISA It was found that 7 of 31 VD patients (28%),10 of 42 ICVD patients (23%) and 1 of 30 Controls(3%) had a significantly elevated aCL 1evels, there were a significantly deference between the two groups and controls(P<0 0 5),either VD patients or ICVD patients who didn't suffer SLE This suggests the aCL may be associated with VD,the mechanism probably similar to ischemia Cerebra1 Vascular diseases
出处
《山东医药》
CAS
北大核心
2001年第19期3-5,共3页
Shandong Medical Journal
关键词
抗磷脂抗体
血管性痴呆
脑梗死
ELISA
Antiphospholipid antibodies Vascular dementia Cerebral infarction
