摘要
以酶联免疫吸附法对４３例缺血性脑血管病患者和４６例非缺血性脑血管病患者测定血清抗心肌磷脂抗体（ａＣＬ），阳性率分别为１８．６％和２．２％，差异显著（Ｐ＜０．０５）。前者患高血压、糖尿病、高血脂和有吸烟史者略高于后者，但差异无显著性。检查证实ａＣＬ阳性的缺血性脑血管病患者均无ＳＬＥ。本研究提示，ａＣＬ与缺血性脑血管病有关，对ａＣＬ的有关发病机制和治疗方法作了探讨。
AbstractForty-three patients with ischemic cerebral vascular diseases and forty-six controls were ex-amined for anticardiolipin(aCLs)by an enzyme-linked immunosorbent assay(ELLSA).Elevated titers of aCLs were found in 18.6% of stroke and TIA patients, but only in 2.2% of age-matched controls. The rate in the patients suffered also from hypertension,hyperlipidemia and cigarrette use in the cerebral ischemia group were slightly higher than in the controls,but the dif-ference was not significant.The patients with elevated aCLs titers did not have systemic lupus ery-thematous(SLE).This study suggests that aCLs are strongly associated with an immunomediated cerebral ischemia.The pathogenetic mechanism and the therape utic trials for a high aCLs are dis-cussed.
出处
《临床神经病学杂志》
CAS
1995年第1期32-34,共3页
Journal of Clinical Neurology
