摘要
研究了不同酸碱条件下 8种喹诺酮类药物的荧光特性。发现了在不同pH介质中喹诺酮类药物的荧光波长和荧光强度的变化规律 ,并对喹诺酮类药物质子化作用及互变异构现象与荧光性质的相关性进行了考察。确定了不同酸碱条件下的两种发光形体 ,进而对相应的变化机理进行了探讨。
The fluorescence characteristics of 8 kinds of quinolone in different pH medium were studied.Rules of wavelength and intensity of the fluorescence in different pH medium were discovered.The correlation between the protonation,tautomerism and luminescence characteristics of quinolone are studied.It is found that in pH 6-8 or 2-4 there are two luminescence species.By this, the new view is respresented that the change of luminescence characteristics is arised from the protonation and toutomerism of quinolones in different pH medium and the material point of luminescence developed in equiliblium system of tautomerizm.Additionly,the correlation between the protonation,toutomerism and luminescence is futher discussed.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2001年第4期518-520,共3页
Spectroscopy and Spectral Analysis
基金
国家自然科学基金 (批准号 :2 98750 1 6)
山西省自然科学基金 (批准号 :2 0 0 1 1 0 1 6)资助课题
