摘要
本文着重介绍了氨基酸-、多肽-环糊精连接物的合成、分子识别和自组装,对环糊精及其衍生物与氨基酸、多肽的包合行为、异构体识别和仿酶合成作了简要概述。
Many kinds of modified cyclodextrins (CDs) bearing the functions such as catalytic activity, membrane permeability and molecular recognition sensor, have been synthesized and investigated. In order to further realize a supramolecular recognition system and develop new functional mateials based on cyclodxtrins and amino acids or peptides, we have designed and synthesized a series of CD-amino acid conjugates and investigated their affinity towards small peptide molecules. This paper summarized recent progresses on the synthesis and molecular recognition of amino acid- or peptide-cyclodextrin conjugates and discussed the inclusion behaviour or self-assembly of cyclodextrins and their derivatives with some vips such as amino acids or peptides.
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2001年第4期457-470,共14页
Chinese Journal of Inorganic Chemistry
基金
国家自然科学杰出青年基金资助项目(No.29925102)
