摘要
目的 :研究复方黑蚂蚁胶囊的药理作用。方法 :制造大鼠佐剂性关节炎模型、小鼠迟发性超敏反应 (DTH)模型和醋酸扭体疼痛模型 ,观察复方黑蚂蚁胶囊的药理作用。结果 :复方黑蚂蚁胶囊可明显抑制完全弗氏佐剂所致大鼠原发性和继发性炎症 ;对DNCB引起小鼠耳肿胀有明显抑制作用 ;可明显减少醋酸所致小鼠扭体次数。结论 :复方黑蚂蚁胶囊对大鼠佐剂性关节炎有抗炎作用 ;对DNCB所致小鼠DTH反应有明显抑制作用 ;
Objective: To study the pharmacologic effects of Compound Black Ant Capsules. Methods: The adjuvant arthritis model of rats (AA rats), delayed hypersensitivity (DTH) model and the pain model induced by acetic acid in mice were used. Results: Compound Black Ant Capsules could significanty inhibit the primary and secondary inflammation of rats induced by the complete Freund's adjuvant, inhibit the ear edema induced by DNCB in mouse and decrease the number of writhes of mouse caused by acetic acid.Conclusion: Compound Black Ant Capsules have the anti inflammatory effect on DTH arthritis and analgesic effect, and inhibit mouse DTH reaction induced by DNCB.
出处
《中成药》
CAS
CSCD
北大核心
2001年第3期202-204,共3页
Chinese Traditional Patent Medicine
