摘要
目的:探讨臭氧联合乳杆菌胶囊治疗阴道炎的临床疗效及安全性。方法:选择阴道炎患者418例,采用随机数字表法分为臭氧组(n=140)、乳酸杆菌组(n=139)和联合组(n=139),臭氧组采用臭氧治疗,乳酸杆菌组采用乳酸杆菌胶囊治疗,联合组联合臭氧和乳酸杆菌治疗。观察三组患者的症状缓解时间及治疗后1个月时阴道pH值、临床疗效,治疗后3个月时复发情况及治疗期间不良反应情况。结果:联合组治疗后1个月pH值明显低于臭氧组和乳酸杆菌组(P=0.00);治疗后1个月,联合组治愈率及总显效率明显高于臭氧组及乳酸杆菌组(P=0.02);治疗后3个月,联合组复发率低于臭氧组、乳酸杆菌组(P=0.03);三组均未出现明显的不良反应。结论:臭氧联合乳酸杆菌治疗阴道炎可明显提高总体疗效,安全可靠,值得临床借鉴。
Objective:To investigate the clinical efficacy and safety of ozone combined with lactobacillus capsule in the treatment of vaginitis .Method:418 cases of patients with vaginitis were selected and randomly divided into ozone group(n=140),lactobacillus group(n=139) and combination group (n=139).Ozone group was treated with ozone,lactobacillus group was treated with lactobacillus capsule,combination group was treated by ozone combined with lactobacillus capsule.The symptomatic relief time,vaginal pH value clinical efficacy after treatment 1 month were observed,recurrence situation and adverse reactions were observed after treatment 3 months.Result:The vaginal pH value at 1 month after treatment of combination group was significantly lower than that of ozone group and lactobacillus group(P=0.00);at 1 month after treatment,the cure rate and total effective rate were significantly higher than that of ozone group and lactobacillus group(P=0.02);at 3 months after treatment,the recurrence rate of combination group was lower than that of ozone group,lactobacillus group(P=0.03);There was no obvious adverse reaction in three groups.Conclusion:Treating vaginitis by ozone combined with lactobacillus capsule can significantly improve the overall curative effect,it is safe and reliable,worthy of clinical reference.
出处
《中外医学研究》
2014年第12期45-46,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
臭氧
乳杆菌胶囊
阴道炎
Ozone
Lactobacillus capsule
Vaginitis