摘要
目的 观察低能量氦氖激光血管内照射 (ILIB)对脑梗塞患者白细胞粘附功能 (LAF)和血清可溶性细胞粘附分子 - 1(sICAM - 1)水平的影响。方法 脑梗塞患者 6 6例 ,30例单纯应用药物治疗 (常规组 ) ,36例在药物治疗的基础上加用ILIB治疗 (ILIB组 )。检测两组患者治疗前、治疗后5 ,10d后LAF和血清sICAM - 1浓度 ,并对患者治疗前后的临床神经功能缺损程度及临床疗效进行评价。结果 急性脑梗塞患者LAF和血清sICAM - 1浓度明显高于正常对照组 (t=16 .5 0～ 17.94,P <0 .0 0 1)。常规组治疗后LAF和血清sICAM - 1浓度降低 ,仅在治疗 10d时差异有非常显著性(t=3.18,P <0 .0 1;t=3.96 ,P <0 .0 0 1) ,而ILIB组治疗后 5d及 10d时LAF和血清sICAM - 1浓度均明显降低 (t =4.48～ 12 .72 ,P <0 .0 0 1) ,且明显低于同期常规组 (t =2 .6 7～ 7.81,P <0 .0 1或0 .0 0 1)。ILIB组比常规治疗组患者出现神经功能明显恢复的时间较早 ,治疗有效率高 (χ2 =4.48,P <0 .0 5 )。结论 ILIB能降低脑梗塞患者LAF和血清sICAM - 1浓度 。
Objective To investigate the effect of intravascular He-Ne laser irradiation on blood(ILIB) for leukocyte adhesion function(LAF) and serum soluble intercellular adhesion molecule-1 (sICAM-1) in cerebral infarction(CT) patients. Methods 30 CI cases were treated with drug treatment(group A);other 36 cases,based on the drug treatment,received the ILIB therapy(group B) once a day for 10 times .another 40 healthy subjects were as control group.The LAF and sICAM-1 concentrations were measured before treatment and after the 5th and 10th day of treatment. Results The LAF and sICAM-1 concentrations in CI patients were obviously higher than those of control group(t=16.50～ 17.94 ,P<0.001).In group A,the LAF and sICAM-1 concentrations were significantly decreased in the 10th day after treatment(t=3.18,P<0.01;t=3.96,P<0.001),but,in group B,they presented on the 5th and 10th day after ILIB treatment(t=4.48～12.72,P<0.001).However,these parameters of group B were obviously lower than those of group A in the same stage(t=2.67～7.81,P<0.01 or 0.001) .While the effective rate( 72.22%) of group B was higher than that of group A(46.67%)(χ 2= 4.48 ,P<0.05). Conclusion These findings indicate that the ILIB therapy can decrease the LAF and sICAM-1 concentrations in CI patients and it is one of those mechanisms for treating CI patients probably.
出处
《中华理疗杂志》
2001年第1期17-19,共3页
Chinese Journal of Physical Therapy
