摘要
目的 :探讨血管紧张素转化酶 (ACE)活性改变在妊高征发生、发展中的作用。方法 :选择轻、中、重度妊高征病人各 10例为实验组 ,正常妊娠妇女 30例为对照组 ,用马尿酸微量比色法检测血清中 ACE活性 ,并进行对比分析。结果 :实验组 ACE活性明显高于对照组 ,妊高征患者的平均动脉压、水肿程度、尿蛋白及尿酸水平与 ACE活性存在正相关。结论 :血清 ACE活性升高与妊高征的发生。
Objective:Our purpose was to investigate the function of angiotensis converting enzyme(ACE) in the occurrence and development of pregnancy induced hypertension(PIH). Methods:The study group included 30 pregnant women diagnosed with PIH( 10 mild, 10 moderate, 10 severe). Thirty healthy pregnant women were selected as the control group. The serum was assayed for the activity of ACE by using color comparison method, hippuric acid used as the substrate. Results:The activity of ACE of the study group was significantly higher than that of the control group. Significantly positive correlationships existed between mean blood pressure, degree of adema, level of urine protein,and uric acid. Conclusion:The elevation of serum activity of ACE is related to the occurrence and development of PIH.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2001年第1期67-71,共5页
Journal of China Medical University
