摘要
朗格汉斯细胞(LC)作为一种皮肤免疫细胞,在摄取、处理和递呈抗原,诱导T细胞反应等方面发挥巨大作用。LC在皮肤中的免疫功能受到诸多因素的影响,明确LC在皮肤免疫中的作用机制,有利于治疗相关的皮肤疾病。本文对LC的抗原呈递作用、LC迁移与成熟的影响因素进行综述。
As a kind of skin immune cell, Langerhans cell （ LC ） plays important role （s） in antigen uptaking, process- ing, presenting and inducing T cell responses. Since the immune function of LC in skin is affected by many factors, understanding the mechanism of LC in skin immune system will shed lights to the treatment of related skin diseases. This review summarized the influencing factors on LC antigen-presenting, LC migration and LC maturation.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2014年第3期304-306,共3页
The Chinese Journal of Dermatovenereology
基金
广东省科技计划项目(No.2012B060300030)
关键词
朗格汉斯细胞
皮肤免疫
抗原递呈
Langerhans cells
Cutaneous immune
Antigen-presenting
