摘要
目的了解医院8年育龄女性生殖道感染无乳链球菌的情况及耐药性，为临床合理用药提供依据。方法对2004年1月～2011年12月临床送检的25～35岁年龄段女性生殖道标本进行常规细菌培养鉴定，并对无乳链球菌进行药敏分析。结果无乳链球菌的检出率呈下降趋势；无乳链球菌对氨苄西林、万古霉素、利奈唑烷均高度敏感，未发现中介或耐药菌株；青霉素耐药率从0～2．94％；头孢噻肟的耐药率从0～2．90％；左氧氟沙星从23．91％～42．03％；甚至四环素的耐药率从84．00％～100．0％；而同时红霉素、克林霉素的耐药率逐年上升，分别从47．50％、32．00％至85．71％、83．12％。结论临床妇科对育龄女性引起的无乳链球菌感染应引起充分重视，并根据药敏结果合理选择抗菌药物，避免耐药菌株产生。
OBJECTIVE To investigate the status of the reproductive tract infections caused by Streptococcus agalactiae in reproductive age women and the drug resistance so as to guide the reasonable clinical medication. METHODS The clinical retrospective tract specimens obtained from the women age between 25 and 35 years old who were enrolled the hospital from Jan 2004 to Dec 2011 were cultured, then the bacterial identification was performed, and the drug susceptibility of the S. agalactiae was analyzed. RESULTS The detection rate of the S. agalactiae showed a downward trend, and the S. agalactiae was sensitive to ampicillin, vancomycin and linezolid, no intermediate or drug resistant strains have been found. The drug resistance rate to penicillin varied from 0 to 2. 94%, eefotaxime from 0 to 2.90%, levofloxacin from 2a. 91% to 42.03%, and tetracycline from 84.00% to 100.00%; the drug resistance rates to erythromycin and clindamycin increased year by year, which increased from 47.50% to 85.71M and from 32.00% to 83.12% ,respectively. CONCLUSION It is necessary for the clinic to pay enough attention to the reproductive tract infections caused by S. agalactiae and reasonably use antibiotics based on the results of drug Susceptibility testing so as to avoid the emergence of drug resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第22期5612-5614,共3页
Chinese Journal of Nosocomiology
基金
国家自然科学基金(81272067)
关键词
无乳链球菌
生殖道
耐药
感染
Streptococcus agalactiae
Reproductive tract
Drug resistancel Infection
