摘要
目的分析新生儿B组溶血性链球菌败血症的临床特点及耐药性，为临床治疗提供依据。方法对2001年1月至2011年8月在我科住院治疗经血培养确诊的7例新生儿B组溶血性链球菌败血症患儿的临床资料、药物敏感试验结果进行回顾性分析。结果早发感染4例，晚发感染3例；白细胞减少6例，C反应蛋白升高6例，并发化脓性脑膜炎4例，感染性休克3例，弥散性血管内凝血2例。所有菌株对青霉素、万古霉素、利奈唑烷均敏感。结论应重视新生儿B组溶血性链球菌败血症，青霉素及万古霉素对该菌敏感性较高。
Objective To analyze the clinical characteristics and resistance of group B hemolytic streptococcus septicemia in neonates, and to provide the evidence for clinical treatment. Methods 7 neonates with group B hemolytic streptococcus septicemia hospitalized from Jan. 2001 to Aug. 2011 were enrolled in this study. The clinical data and laboratory results of antimicrobial sensitivity were analyzed retrospectively. Results There were 4 cases of early-onset infection and 3 cases of late-onset infection,6 cases with leukopenia,6 cases with c-reactive protein elevated,4 cases with suppurative meningitis,3 cases with septic shock and 2 cases with disseminated intravascular coagulation. All strains were sensitive to penicillin, vancomycin and linezolid. Conclusion Attention should be paid to neonatal group B hemolytic streptococcus septicemia. Penicillin and vancomycin are first choice for this type of infection.
出处
《中国综合临床》
2012年第5期549-550,共2页
Clinical Medicine of China
关键词
败血症
B组溶血性链球菌
新生儿
Septicemia
Group B hemolytic streptococcus
Neonate
