摘要
[目的]比较重症监护病房(ICU)与普通病房不动杆菌的感染及耐药情况,以期指导临床合理用药。[方法]对临床标本进行常规细菌培养鉴定,以K-B法进行药物敏感性试验。[结果]从4 260份临床标本中分离出不动杆菌290株,分离率为6.8%,其中ICU病房构成比最高为29.7%(86/290)。在11种抗生素中,亚胺培南的体外抗菌活性最好。除复方新诺明和亚胺培南外,ICU中不动杆菌的耐药率明显高于普通病房的耐药率(P﹤0.05)。[结论]亚胺培南是治疗不动杆菌的首选药物。ICU中不动杆菌的耐药性较高应引起高度重视。
[Objective]To compare the drug resistance of acinetobacter isolated from intensive care unit（ICU）and general ward,and to provide experimental data for rational use of drug in clinic.[Methods]Bacterial culture and identification of clinical specimens were conducted,and K-B method was used to perform drug sensitivity test.[Results]290 strains of acinetobacter were isolated from 4 260 clinical specimens,the isolating rate was 6.8%.Among them,clinical specimens from ICU were the most,accounting for 29.7%（86/290）.Imipenem had the best antibacterial activity in vitro among 11 kinds of antibiotics.The drug resistance rate of acinetobacter from ICU was obviously higher than that from general ward（P﹤0.05）except for Imipenem and SMZ.[Conclusions]Imipenem is the choice drug for the treatment of acinetobacter infection.It should be emphasized that the drug resistance of acinetobacter isolated from ICU is rather high.
出处
《现代预防医学》
CAS
北大核心
2007年第23期4581-4582,共2页
Modern Preventive Medicine
