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星形胶质细胞在癫痫发病中的作用 被引量：11

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摘要 目前临床上的抗癫痫药物都是通过调节神经元活动起作用的,但是仍有近三分之一的癫痫患者发展成为难治性癫痫。近年来随着对癫痫发生机制的深入研究,星形胶质细胞在癫痫中的作用得到了国内外研究者的关注。大量研究发现,癫痫的形成、发作过程常常伴随星形胶质细胞明显的功能改变,这提示星形胶质细胞在癫痫的发病机制中起着重要作用。因此,对星形胶质细胞在癫痫发病机制中的作用进行深入研究,有可能发现新的抗癫痫药物作用靶点,对癫痫治疗策略产生深刻影响。
作者 陈忠 孙红柳
机构地区 浙江大学药学院药理学教研室 山东滨州医学院药理教研室
出处 《浙江大学学报（医学版）》 CAS CSCD 北大核心 2013年第3期245-252,共8页 Journal of Zhejiang University(Medical Sciences)
基金 国家杰出青年科学基金(30725047) 浙江省卫生高层次创新人才培养工程项目(419000-710908) 浙江省重点科技创新团队计划资助(2011R50014)
关键词 癫痫 病理生理学 星形胶质细胞 病理学
分类号 R742.1 [医药卫生—神经病学与精神病学]
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参考文献63

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二级参考文献31

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共引文献4

同被引文献128

引证文献11

二级引证文献84

浙江大学学报（医学版）
2013年 第3期

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