摘要
目的探讨增液承气汤对2型糖尿病动脉粥样硬化颈动脉内膜-中层厚度(IMT)及血脂的影响。方法在常规糖尿病西医治疗基础上采用增液承气汤治疗2型糖尿病动脉粥样硬化178例,观察治疗前后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)和血浆脂蛋白α(Lpα)水平,同时进行彩色多普勒超声检查,比较颈动脉IMT水平。结果治疗前后TC、TG、LDL、HDL、Lpα水平比较差异均有统计学意义(P<0.05),颈动脉IMT治疗前为(0.91±0.13)mm,治疗后为(0.77±0.14)mm,比较差异有统计学意义(P<0.05)。结论增液承气汤能改善2型糖尿病动脉粥样硬化TC、TG、LDL、HDL、Lp(α)及颈动脉IMT指标,同时血脂水平是2型糖尿病动脉粥样硬化的危险因素之一,与颈动脉IMT相关性强。
Objective To research the effect of Zengqichengqi decoction on carotid artery intima-media thickness（IMT） and lipid of type 2 diabetes artery atherosclerosis.Methods 178 patients of type 2 diabetes artery atherosclerosis were treated by Zengqichengqi decoction on the basis of conventional therapy.TC,TG,LDL,HDL,LP（alpha） and carotid IMT levels were compared before and after treatment.Results There were significant differences between before and after treatment on the levels of TC,TG,LDL,HDL and Lp（alpha）（P〈0.05）.Carotid IMT after treatment（0.77±0.14 mm） was lower than that in before treatment（0.91±0.13 mm,P〈0.05）.Conclusion Zengqichengqi decoction can improve the indexes of TC,TG,LDL,HDL,Lp（alpha） and carotid IMT in type 2 diabetes artery atherosclerosis,lipid levels is one of the risk factors for type 2 diabetes atherosclerosis,and there was a strong correlation with carotid IMT.
出处
《河北中医》
2013年第3期370-372,共3页
Hebei Journal of Traditional Chinese Medicine
关键词
增液承气汤
动脉硬化
糖尿病
2型
颈动脉
脂类
脂蛋白类
中药疗法
Zengyechengqi decoction
Arteriosclerosis
Type 2diabetes
Carotid artery
Lipids
Lipoproteins
Traditional Chinese medicine therapy
