摘要
目的探讨血清脂联素、超敏C反应蛋白与2型糖尿病动脉粥样硬化病变程度的相关性。方法分别检测98例2型糖尿病动脉粥样硬化患者和40例正常对照者血清中脂联素、超敏C反应蛋白水平变化,并比较与动脉粥样硬化病变程度的相关性。结果糖尿病动脉粥样硬化组脂联素水平明显低于正常对照组、超敏C反应蛋白水平明显高于正常对照组,2组比较差异有统计学意义(P<0.05)。并且,随着动脉粥样硬化病变程度的增加,血清脂联素水平逐渐降低(P<0.05),超敏C反应蛋白水平逐渐增高(P<0.05)。结论血清脂联素、超敏C反应蛋白与动脉粥样硬化病变程度密切相关,两者可用作判断糖尿病动脉粥样硬化病变程度的指标。
Objective To explore the relationship between serum adiponcetin,high -sensitive C reactive protein, and type 2 diabete atherosclerosis. Methods Serum adiponcetin and high - sensitive C reactive protein were detected in 98 cases 0f type 2 diabete atherosclerosis and 40 cases Of healthy controls. Results The level of serum adiponcetin in the type 2 diabete atherosclerosis group was significantly lower than that in the control group （ P 〈 0.05 ） and：the level of Serum high - sensitive C reactive protein was significantly higher than that in the control group （ P 〈 0.05 ）. Moreover, with aggravation of atherosclerosis,the level of serum adiponcetin was gradually degraded （ P 〈 0.05 ） and the level of serum high -sensitive C reactive protein was gradually increased （ P 〈 0.05）. Conclusion The levels of serum adiponcetin and high .-sensitive C reactive protein are closely associated with atherosclerosis and can be used as indexes for predicting the degree of diabete atherosclerosis.
出处
《河北医科大学学报》
CAS
2010年第12期1471-1473,共3页
Journal of Hebei Medical University
关键词
糖尿病
2型
动脉硬化
血清
diabetes mellitus, type 2
arteriosclerosis
serum
