摘要
目的探讨血清超敏C反应蛋白(hs-CRP)水平与颈动脉粥样硬化斑块稳定性之间的关系。方法 86例颈动脉粥样硬化患者根据颈动脉超声多普勒检测斑块回声特征分为不稳定性斑块(易损斑块组)38例和稳定性斑块(非易损斑块组)48例。另选40例无颈动脉粥样硬化斑块者作为正常对照组。采用ELISA法检测血清hs-CRP水平。结果颈动脉粥样硬化患者血清hs-CRP水平明显高于正常对照组,差异有显著统计学意义(P<0.05)。颈动脉易损斑块组血清hs-CRP水平高于非易损斑块组,两组比较差异亦有显著统计学意义(P<0.05)。结论血清hs-CRP水平与颈动脉粥样硬化斑块稳定性相关,提示血hs-CRP水平可作为动脉粥样硬化程度及斑块稳定性的指标之一。
Objective To investigate the relationship between the level of high sensitivity C-reactive protein(hs-CRP) and the stability of carotid atherosclerosis plaque.Methods Eighty-six patients with carotid atherosclerotic plaque were assessed by carotid color ultrasonography and divided into the stable plaque group(38 patients) and the unstable plaque group(48 patients) according to the features of atherosclerotic plaques.Forty cases without carotid atherosclerotic plaques were selected as the normal control group.Serum level of hs-CRP was assessed by ELISA.Results Serum hs-CRP levels in patients with carotid atherosclerosis were significantly higher than that in the controls(P<0.05).The levels of hs-CRP in patients with unstable plaque were higher than that in patients with stable plaque(P<0.05).Conclusion The relationship between the hs-CRP and the stability of the carotid atherosclerotic plaques suggests that hs-CRP can be used as a marker of the degree and stability of carotid atherosclerosis.
出处
《神经病学与神经康复学杂志》
2010年第2期75-77,共3页
Journal of Neurology and Neurorehabilitation
关键词
超敏C反应蛋白
颈动脉粥样硬化
斑块
high sensitivity C-reactive protein
carotid atherosclerosis
plaque
