期刊文献+

分子靶向药物治疗非小细胞肺癌的临床研究刍议

暂未订购
导出
摘要 目的:对分靶向药物在非小细胞肺癌治疗的临床研究做了相关介绍。方法:结合国内外相关资料进行了分析研究。结果:在临床治疗当中,作用在表皮生长因子受体药物和环氧合酶抑制剂及抗血管生成药物的综合应用,明显改善了患者的症状和生存期。结论:随着现代医学的进步以及分子生物学理论和技术的进展,采用针对肺癌发病机制的靶向分子生物学研究,为更多的肺癌患者的治疗开辟了一种全新导热治疗途径。
作者 张涛
出处 《北方药学》 2013年第5期104-105,共2页 Journal of North Pharmacy
  • 相关文献

参考文献7

二级参考文献50

  • 1卞爱娜,高云华,谭开彬,刘平,曾功君,张馨,刘政,高会广.人肝癌靶向脂质体微泡造影剂的鉴定及免疫学性质研究[J].中华超声影像学杂志,2004,13(9):696-699. 被引量:14
  • 2JEMAL A,TIWARI R C,MURRAY T,et al.Cancer statistics[J].CA Cancer J Clin,2004,54:8-29.
  • 3BERCHUCK A,RODRIGUEZ G C,KAMEL A,et al.Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer.Ⅱ.Correlation of receptor expression with prognostic factors in patients with ovarian cancer[J].Am J Obstet Gynecol,1991,164:745-750.
  • 4CHAN J K,PHAM H,YOU X J,et al.Suppression of ovarian cancer cell tumorigenicity and evasion of cisplatin resistance using a truncated epidermal growth factor receptor in a rat model[J].Cancer Res,2005,65:3243-3248.
  • 5MAIHLE N J,BARON A T,BARRETTE B A,et al.EGF/ErbB receptor family in ovarian cancer[J].Cancer Treat Res,2002,107:247-258.
  • 6WISCHNEWSKI F,PANTEL K,SCHWARZENBACH H,et al.Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1,-A2,-A3,and -A12 in human cancer cells[J].Mol Cancer Res,2006,4(5):339-349.
  • 7PATZEL V,RUTZ S,DIETRICH I,et al.Design of siRNA producing unstructured guide-RNAs results in improved RNA interference efficiency[J].Nat Biotechnol,2005,23(11):1440-1444.
  • 8RAND T A,PETERSEN S,DU F,et al.Argonaute2 cleaves the antiguide strand of siRNA during RISC activation[J].Cell,2005,123(4):621-629.
  • 9NIELSEN J S,JAKOBSEN E,HOLUND B,et al.Prognostic significance of p53,Her-2,and EGFR overexpression in borderline and epithelial ovarian cancer[J].Int J Gynecol Cancer,2004,14(6):1086.
  • 10ALPER O,BERGMANN-LEITNER E S E S,et al.Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells[J].J Natl Cancer Inst,2001,93(18):1375.

共引文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部