摘要
目的 探讨ITP方案治疗腺癌的疗效及其副作用。方法 15例晚期腺癌患者 ,化疗方案为THP2 5mg/m2第 1天静注 ,DDP10 0mg/m2 分 1至 2次于第 1天及第 2天静滴 ,IFO 2g/d连续 3至 5天于第 3至 7天静滴 ,并用尿路保护剂巯乙黄酸钠 40 0mg于IFO后 0、4、8h输注。每周期间隔 2 1～ 2 8天。 结果 近期总缓解率 93 .33 % ,其中CR1例 ,PR13例 ,主要副作用为骨髓抑制。结论 ITP方案是治疗晚期腺癌疗效好且能耐受的治疗方案。
Objective To evaluate both the therapeutic and the side effect of ITP regimen in advanced adenocarcinoma.Methods 15 cases of advanced adenocarcinoma available.were given chemotherapy conisting of THP at 25mg/m 2 iv on d 1(on the first day),DDP at 100mg/m 2 iv on d 1 and d 2,IFO at 2g/d iv gtt for three or five days from d 3 to d 7.Meanwhile measna 400mg iv three times every 4h right after the administration of IFO.The therapeutic interval was 21 days to 28 days.Results Overall PR was 93.33%,while CR and PR was observed in 1 and 13 patietns respectively.The main side effect was myleosuppression.Conclusions ITP regimen is not only effective but also well tolerated by patients with advanced adenocicinoma. [
出处
《中国肿瘤临床与康复》
2000年第5期88-89,共2页
Chinese Journal of Clinical Oncology and Rehabilitation
