摘要
本文报道用调整后的FAM方案治疗53例晚期腺癌,获得疗效完全缓解3例,部分缓解17例,总有效率为37.7％。其中以乳腺癌和胃癌的疗效最佳,有效率分别为66.7％和48.4％,肺癌和结直肠癌的疗效均差。本方案的主要毒性作用为胃肠道反应及骨髓抑制,但多属I～Ⅱ度,患者均能耐受。
5 3 advanced adenocarcinoma were treated with adjusted FAM(5-Fluorouracil , Adriamycin, Mitomycin), regimen and the overall response rate (RR) was 37.7% ( CR3, and PRl7). The best result was seen in mammary and gastric carcinoma (RR= 66.7% and 48.4% respectively), but the response rates for lung and Colo-rectal carcinoma were poor.The major toxic side effects were gestrointestinal tract and myelosuppfession , but the great majority was limited to 1-11 grade, and patients were tolerable.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1990年第3期194-196,共3页
Chinese Journal of Cancer
