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PC-MR不同解剖定位测量中脑导水管脑脊液流动的可复性研究 被引量:10

The research about repeatability of CSF flow measurements of cerebral aqueduct on different anatomical localization utilizing PC-MR
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摘要 目的探讨同一解剖位置不同检查者测量结果间的相关性及可复性。方法选取32例健康志愿者,其中男15例,女17例,年龄18~30岁,平均(25.4±3.4)岁。应用3.0TMR两次测量中脑导水管不同解剖位置的脑脊液(CSF)流动。由两位医师先后对同一志愿者进行独立扫描,所有图像由另一医师进行后处理。选用T2WI正中矢状面定位,先后垂直导水管入口段、中间段、出口段进行扫描。在导水管显示面积最大的幅度图像上沿其边缘绘制ROI,重复3次取其结果平均值。取收缩期向下峰值流速(PPV)、舒张期向上峰值流速(PNV)及绝对每搏出量(ASV)进行对比分析。取2位医师测量结果的平均数用于比较不同解剖定位对测量结果的影响。结果不同解剖定位间平均PPV、PNV存在统计学差异,上段高于下段(P<0.05),两两均数比较,入口段与出口段流速存在差异(P<0.05);而ASV三者间无差异(P>0.05)。不同医师测量相同解剖定位时,两次PPV测量结果相关性以中间段最高,相关系数r=0.94,出口段r=0.82,入口段r=0.78。结论①中脑导水管不同解剖位置的CSF流速存在差异,上段流速高于下段,而ASV无差异;②导水管中间段测量结果可复性最佳,可作为理想的测速位置。 Objective To explore the correlation and repeatability of the measured results on the same anatomical localization by different surveyor. Methods 32 healthy volunteers were selected for research, including 15 males and 17 female, aged 18- 30 yeas old, mean 25.4 ±3.4 yeas old. We measured CSF flow of the aqueduct with 3T MR on different anatom-ical localization repeatedly. All volunteers were examined by two physicians independently and all images were postpro cessed by another physician. The localizer was placed perpendicular to the inlet, ampulla, pars posterior of the aqueduct on the median sagittal T2-weighted image. The region of interest (ROD was drew in the amplitude image when the aqueduct could be seen optimally, the result was measured thrice and general average was calculated. Evaluated parameters were the peak positive velocity (PPV), the peak negative velocity (PNV), and the absolute stroke volume (ASV) were selected for comparative analysis. We took the average by the two physicians, and compared the influences of different anatomical localization. Results The PPV and PNV showed significant difference in different anatomical localization, the flow rates of upper segment were faster than the lower ones ( P 〉0.05), but ASV showed no statistical difference ( P 〈0.05), when compared each other, the flow rates of the inle were faster than the pars posterior of the aqueduct ( P 〈0.05). As for the same anatomical position measured by different surveyor, the correlation of results showed most compacted on ampulla and the coefficient correlation r = 0.94, r =0.82 on the pars posterior, r = 0.78 on the inlet. Conclusion ①The flow rates showed significant difference in different anatomical localization, the upper segments were faster than the lower ones ( P d0.05), ASV showed no statistical difference ( P 〉0.05) ②The metered results of ampulla showed the best repeat ability, the ampulla of cerebral aqueduct could become the desirable anatomical localization of PC-MR measurement.
出处 《医学影像学杂志》 2013年第3期355-358,共4页 Journal of Medical Imaging
关键词 相位-对比磁共振 解剖定位 中脑导水管 脑脊液流动 PC-MR Anatomical localization Cerebral aqueduct CSF flow
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参考文献14

  • 1Krauss JK, Regel JP, Vach W, et al. Flow void of cerebro spinal fluid inidiopathic normal pressure hydrocephalus of the elderly: can it predict outcome after shunting ? [J].Neuro- surgery, 1997, 40: 67-73.
  • 2包雪梅,黄峰.PC-MRA在脑血管病变中的临床应用[J].医学影像学杂志,2009,19(5):622-624. 被引量:5
  • 3Lee JH, Lee HK, Kim JK, et al. CSF flow quantification of the cerebral aqueduct in normal volunteers using phase con-trast cine MR imaging [J]. Korean J Radiol, 2004,5: 81-86.
  • 4Kapsalaki E, Svolos P, Tsougos I, et al. Quantifi cation of normal CSF flow through the aqueduct using PC-Cine MRI at 3T [J]. Acta Neurochir Suppl, 2012, 113 : 39-42.
  • 5Abbey P, Singh P, Khandelwal N, et al. Shunt surgery effects on cerebrospinal fluid flow across the aqueduct of syl- vius in patients with communicating hydrocephalus [J]. J Clin Neurosci, 2009, 16: 514-518.
  • 6朱晓黎,沈天真,陈星荣.正常中脑导水管脑脊液流动磁共振定量研究[J].医学影像学杂志,2004,14(11):875-878. 被引量:19
  • 7Battal B, Kocaoglu M, Bulakbasi N, et al. Cerebrospinal fluid flow imaging by using phase-contrast MR technique [J]. The British Journal of Radiology, 2011, 84 : 758-765.
  • 8Stoquart-E1 Sankari S, Lehmann P, Gondry-Jouet C, et al. Phase-contrast MR imaging support for the diagnosis of aque- duetal stenosis [J]. AJNR, 2009, 30: 209-214.
  • 9Algin O, Hakyemez B, Parlak M. Phase-contrast MRI and 3D-CISS versus contrast-enhanced MR cisternography on the evaluation of the aqueductalstenosis [J]. Neuroradiology, 2010,52: 99-108.
  • 10Stavros SM, Jackson A. Changing concepts of cerebrospinal fluid hydrodynamics: role of phase-contrast magnetic reso- nance imaging andImplications for cerebral microvascular dis- ease [J]. American Society for Experimental NeuroTherapeu- tics, 2007, 4: 511-522.

二级参考文献37

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同被引文献73

  • 1曾双林,谭利华.紧张型头痛患者导水管平面脑脊液流动相位对比法磁共振成像研究[J].中南大学学报(医学版),2014,39(2):168-172. 被引量:7
  • 2朱晓黎,沈天真,陈星荣.正常中脑导水管脑脊液流动磁共振定量研究[J].医学影像学杂志,2004,14(11):875-878. 被引量:19
  • 3朱晓黎,沈天真,陈星荣.MR相位对比电影法在正常颈部及颅内大血管血流测量中的应用[J].中国医学影像技术,2005,21(3):365-368. 被引量:17
  • 4李果珍.临床CT诊断学[M].北京:中国科学技术出版社,1997.318-322,327-331,365-368.
  • 5杨正汉,冯逢,王霄英,等.磁共振成像技术指南[M].北京:人民军医出版社,2007:85-88.
  • 6Jiang J, Strother C, Johnson K, etal. Comparison of blood velocity measurements between ultrasound Doppler andaccelerated phase-contrast MR angiography in small arteries with disturbed flow. Phys Med Biol,2011,56:1755-73.
  • 7Baledent O, 6ondry- Meyer ME, etal. Rela Between Cerebrospin Jouet C, tionship al Fluid and Blood DynCAics in Healthy Volunteers and Patients with Communicating Hydrocephalus. Investigative Radiology, 2004, 39:45-55.
  • 8Silverberg GD, Levinthal E, Sullivan EV, et al. Assessment of low-flow CSF drainage as a treatment for AD: results of a randomized pilot study. Neurology, 2002, 59:1139 -1145.
  • 9Bateman GA, Levi CR, Schofield P, et al. Quantitative measurement of cerebral haemodynCAics in early vascuiar dementia and Alzheimer' s disease[J]. Clin Neurosci. 2006,13:563-568.
  • 10Bateman GA. The role of altered impedance in the pathophysiology of normal pressure hydrocephalus, Alzheimer' s disease and syringomyelia. Med Hypotheses , 2004, 63:980-985.

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