摘要
本文收集不同科属、不同产地的板蓝根样品27个、大青叶样品5个。对样品的化学成分进行高效液相色谱分析,获得反映样品整体化学特征的数据,同时选择体外抑菌药理指标进行药理活性测定。用典型相关分析(CCOR)揭示了化学信息和药理指标之间的相关关系,寻找与药理指标密切相关的化学成分,用ISODATA聚类分析技术将32个样品划分为5类。用本文建立的方法评价板蓝根、大青叶的质量,结果良好,正确率为90.6％。
27 samples of indigowoad root and 5 samples of indigowoad leaf from different species and in different habitat were collected.The chemical constituents were analyzed by HPLC.and ten original chemical features as a whole obtained. Meanwhile,ex- trinsic bacteriostasis experiments were carried out for each of the 32 samples.Canonical correlation analysis was applied to the in-tercorrelation between the chemical and the pharmacologic data, and five chemical features were found to be the effective constituents. In the end,the 32 samples were divided into five classes by the fuzzy clustering technique ISODATA(interachive self-organizing data analysis technique A).
出处
《中药材》
CAS
CSCD
2000年第10期609-613,共5页
Journal of Chinese Medicinal Materials
关键词
板蓝根
大青叶
化学模式识别
质量评价
Indigowoad root
Indigowoad leaf
Chemical pattern recognition, Quality evaluation
