摘要
目的 评价尿道内切开或瘢痕电切术后腔内放疗治疗复发性尿道狭窄的近期疗效。 方法 采用尿道内切开或瘢痕电切术后腔内放疗治疗复发性尿道狭窄 17例 ,尿道狭窄长度 0 .8～1.5cm ,术后以192 Ir(铱 )行腔内放疗 ,剂量为 10 0 0～ 15 0 0cGy。 结果 17例平均随访 15个月。 2例于拔除导尿管后仍有不同程度的排尿不畅 ,其中 1例经尿动力学检查后提示为膀胱逼尿肌无力及逼尿肌外括约肌协同失调 ,1例经 3次尿道扩张后排尿通畅 ,15例排尿正常 ,其中 1例于治疗后 3个月复发再次行尿道内切开 ,术后未再复发。最大尿流率 13.9～ 36 .4(19.2± 10 .3)ml/s,平均尿流率9.8～ 2 3 .5 (13 .4± 6 .5 )ml/s。 结论 尿道内切开或瘢痕电切术后腔内放疗有助于预防尿道狭窄复发 ,副作用小 。
Objective To evaluate transurethral incision or transurethral resection of scar followed by intraluminal brachytherapy for recurrent urethral stenosis. Methods From 1998 to 1999,17 cases of recurrent urethral stenosis with a stenosis length of 0.8 to 1.5 cm have been treated by transurethral incision or transurethral resection of scar followed by intraluminal brachytherapy with 192 Ir. The irradiation dose was 1 000 to 1 500 cGy. Results All the patients have been followed up for a mean of 15 months, 2 patients have dysuria while the other 15 present normal voiding. One of the 15 recurred after this procedure and accepted transurethral incision again. The maximum flow rate from 13.9 to 36.4(19.2±10.3)ml/s and the average flow rate ranges from 9.8 to 23.5 (13.4±6.5)ml/s. No secondary urethral bleeding and urethral cancer have been noted. Conclusions Intraluminal brachytherapy following transurethral incision or transurethral resection of scar can avoid recurrence of urethral stenosis effectively.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2000年第10期630-632,共3页
Chinese Journal of Urology
