摘要
目的研究调督通脉针灸法对佐剂性关节炎(AA)大鼠脊神经核因子-κB(NF-κB)表达的影响。方法完全弗氏佐剂诱导Wistar大鼠AA,采用免疫组织化学法检测大鼠脊神经节中NF-κB活性表达。结果针灸第14天采集标本,调督通脉针灸法对AA大鼠脊神经节NF-κB(P65)的高表达活性降低优于普通针灸(P<0.05)。结论调督通脉针灸法能够抑制脊神经节NF-κB的高表达活性,为针灸治疗RA提供更多的理论依据。
Objective To explore the influence of acupuncture through stimulating governor meridian and other meridians for pathological change of the Adjuvant induced arthritis（AA） rats in the spinal ganglia.Methods Complete Freund＇s adjuvant inductive Wistar AA rats,and to observe the joint swelling.To observe the expression of Nuclear factor-kappa B in the spinal ganglia with immunohistochemical method.Results On the 7th and 14th day during the acupuncture can reduce joint swelling of AA rats（P0.05,P0.01）;and other meridians acupuncture is better than the conventional acupuncture（P0.05）.Conclusions The stimulating governor meridian and other meridians acupuncture can inhibit the over-expression Nuclear factor-kappa B in the spinal ganglia ofAArats,Providing the theoretical foundations for clinical treatment for RAacupuncture.
出处
《中国医药指南》
2013年第5期23-24,共2页
Guide of China Medicine
关键词
针灸
脊神经节
佐剂性关节炎
核因子-ΚB
Acupuncture
Pinal ganglia
Adjuvant induced arthritis（AA）
Nuclear factor-kappa B（NF-κB）
