摘要
目的评价调燮丸治疗代谢综合征的临床疗效。方法选择代谢综合征患者62例,维持原治疗方案不变1个月的情况下,再给予患者调燮丸口服,连服2个月。观察治疗后患者血脂、糖化血红蛋白(HbA1C)、空腹胰岛素(FINS)、胰岛素敏感指数(IAI)、体重指数(BMI)以及主要症状的临床疗效。结果患者治疗后头晕、口干、便秘、腹胀、胸闷、急躁易怒等症状明显改善,总有效率均在85%以上。治疗后患者BMI、血脂水平、HbA1C明显降低,FINS、IAI明显升高(P<0.05或P<0.01)。结论调燮丸能够明显改善代谢综合征患者的高血脂状态,促进胰岛素分泌,增加胰岛素敏感性。
Objective To evaluate the clinical effect of Tiaoxie Wan （Chinese medicine for regulating the metabolic functions） on the metabolic syndrome. Methods Under the condition without changing their original treatment, the 62 metabolic syndrome pa tients were administered Tiaoxie Wan for oral taking in succession for 2 months. The blood lipid, glycolated hemoglobin （HbA1C）, fasting insulin （FINS）, insulin action index （IAI）, body mass index （BMI）, and the clinical effect of main symptoms were observed. Results After treatment, the symptoms such as dizziness, dry mouth, constipation, abdominal distention, and hot temper with irritability were significantly relieved, the total effective rate was all above 85%. The BMI, blood lipid, and HbA1C were significantly decreased, while the FINS and IAI were significantly increased （P〈0.05 or P〈0.01）. Conclusion Tiaoxie Wan is effective in improving the high blood lipid state of the patients with metabolic syndrome by increasing insulin secretion and improving insulin sensitivity.
出处
《中医杂志》
CSCD
北大核心
2010年第8期709-710,共2页
Journal of Traditional Chinese Medicine
关键词
代谢综合征
调燮丸
血脂
糖代谢
Metabolic syndrome
Tiaoxie Wan （Chinese medicine for regulating the metabolic functions）
Blood lipid
Glucose metabolism
