摘要
目的对比分析腹腔镜与阴式手术和开腹手术治疗早期子宫内膜样腺癌在术中及术后的临床疗效,为临床医师治疗提供参考。方法选取江西省妇幼保健院2009年5月-2012年5月收治的早期子宫内膜腺癌患者共90例,将其随机分为两组,开腹组45例为传统开腹手术组,腹腔镜组45例为腹腔镜辅助阴式手术组,比较两组间各项指标的差异。结果腹腔镜组手术时间、术中出血量分别为(153.39±34.58)min、(92.66±73.62)ml,开腹组为(206.87±40.80)min、(187.56±101.7)ml,两组差异均有统计学意义(P<0.01);腹腔镜组术后切除淋巴结为(20.1±7.9)个、开腹组切除淋巴结为(23.4±9.8)个,两组差异无统计学意义;腹腔镜组术后住院时间、术后补充治疗间隔时间分别为(8.77±6.89)d、(26.00±14.80)d、开腹组为(9.42±2.25)d、(33.0±20.5)d,两组差异均有统计学意义(P<0.05);腹腔镜组随访期间未发现腹壁转移,术后出现阴道残端转移1例,开腹组在术后死亡1例。结论腹腔镜作为早期子宫内膜样腺癌的治疗术式,术后切口无感染,其临床疗效优于开腹组。
OBJECTIVE To evaluate intraoperative clinical effect and postoperative clinical effect of laparoscopic assisted vaginal hysterectomy(LAVH)on early endometrioid adenocarcinoma so as to guide the clinical treatment. METHODS A total of 90 patients with early stage endometrioid adenocarcinoma, who were treated in the hospital from May 2009 to May 2012, were selected and were randomly divided into two groups. 45 patients were treated with LAVH, other 45 patients were treated with abdominal surgery. The parameters between the two groups were compared retrospectively. RESULTS The operation duration was (153.39 ± 34.58)min in the LAVH group and(206.87±40.80)min in the other group; the intraoperative blood loss was (92.66±73.62)ml in the LAVH group and (187. 56 ± 101. 7)ml in the other group , the difference between the two groups was statistically significant (P〈0.01) ; the number of postoperative lymph nodes was (20.1±7.9) and (23.4±9.8) in the other group, the difference was not statistically significant. The postoperative hospitalization duration was (8.77 ±6.89) d in the LAVH group and (9.42± 2.25)d in the other group, the postoperative interval of replacement therapy was (26.00±14.80)d in the LAVH group and (33.0±20.5)d in the other group,the difference between the two groups was statistically significant(P〈0.05). The abdominal wall metastases had not been found in the LAVH group, however, there was one case with vaginal stump metastases,and one case in the other group died after the surgery. CONCLUSION The LAVH is a feasible and better treatment for the early endometrial cancer, and the intraoperative clinical effect and postoperative clinical effect of LAVH are better than abdominal surgery.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第6期1375-1376,共2页
Chinese Journal of Nosocomiology
基金
江西省卫生厅资助项目(20111101)
关键词
腹腔镜辅助阴式手术
开腹手术
早期子宫内膜样腺癌
Laparoscopic assisted vaginal hysterectomy
Abdominal surgery
Early stage endometrioid adenocarcinoma