摘要
目的探讨组织多普勒Tei指数(Tei index measured by tissue Doppler imaging,t-Tei)联合血清可溶性凝集素样氧化型低密度脂蛋白受体-1(serum soluble lectin-like oxidized low-density lipoprotein receptor,sLOX-1)评价急性冠状动脉综合征(acute coronary syndrome,ACS)患者心功能的临床价值。方法 ACS患者112例(观察组)与体检健康者46例(对照组),均行经胸超声心动图及组织多普勒检测t-Tei指数及左心室射血分数等指标,采用ELISA法检测血清sLOX-1水平,并进行比较。结果观察组t-Tei指数及血清sLOX-1水平均较对照组明显增高(P<0.01);t-Tei指数及血清sLOX-1水平与左心室射血分数呈负相关(P<0.05)。结论 t-Tei指数及血清sLOX-1均能较好反映ACS患者的左心收缩功能,二者联合可用于整体评价ACS患者的心功能情况。
Objective To investigate the effects of Tel index measured by tissue Doppler imaging （t-Tei） and serum soluble lectin like oxidized low-density lipoprotein receptor-1 （sLOX-1） levels on the evaluation of heart function in patients with acute coronary syndrome （ACS）. Methods A total of 112 patients with ACS and 46 healthy controls were detected t-Tel index, left ventricular ejection fraction （LVEF） and other indexes by using echocardiography and tissue Doppler imaging. Serum sLOX-1 level was measured by using EL1SA. Results t Tel index and serum sLOX-1 levels were significantly higher in ACS group than those in control group （P〈0.01）, and were negatively correlated with LVEF （P〈0.05）. Conclusion Both t-Tel index and serum sLOX-1 levels could reflect left systolic heart function well in patients with ACS. Combined examination of them can evaluate the heart function in patients with ACS.
出处
《中华实用诊断与治疗杂志》
2013年第1期40-41,44,共3页
Journal of Chinese Practical Diagnosis and Therapy
