摘要
Rosai-Dorfman病(RDD)又称为窦性组织细胞增生伴巨大淋巴结病,是一种病因不明的良性病变,临床极为罕见,可累及全身淋巴系统,也存在结外病变,其中皮肤是最常见的受累部位。颌面部Rosai-Dorfman病可表现为结内型,亦有结外型,其临床特点和影像学表现缺乏特异性,故需病理检查明确诊断,同时术后需要配合免疫治疗及定期随访。本文报告1例颌面部皮肤RDD复发患者,并结合文献对其临床特点、诊疗及预后进行讨论。
Rosai Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign lesion of unknown etiology. It is extremly rare in clinic, which can affect the lymphatic system. There are also extranodal cases of skin involvement etc. In the maxillofacial region, this disease varied from nodal type to extranodal type. It is hard to diagnose as the clinical and radiological manifestation is not unique. The pathological examination is still the golden standard in diagnosis. The systematic immunotherapy and regular follow-up is necessary. We presented a case of recurrent RDD in maxillofacial region, and reviewed the literatures to discuss the clinical features, pathogenesis, diagnosis, treatment and prognosis of this disease. Supported by Research Fund of Science and Technology Commission of Shanghai Municipality （08DZ2271100）.
出处
《中国口腔颌面外科杂志》
CAS
2013年第1期85-88,共4页
China Journal of Oral and Maxillofacial Surgery
基金
上海市科学技术委员会资助项目(08DZ2271100)~~
