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HLA-E、HLA-F及HLA-G与母胎免疫耐受研究进展 被引量:5

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摘要 母胎免疫耐受现象是一个多系统、多因素的母胎界面免疫活化和抑制的平衡过程,其中以胎儿滋养层细胞HLAI类分子表达及子宫NK细胞活性的调节最引人注目。早在1953年,Billingham等[1]。就已提出“母胎免疫耐受”维持机制假说,认为子宫内形成一个对胎儿有利的免疫豁免环境是妊娠成功的关键。
出处 《医学研究杂志》 2013年第1期178-179,61,共3页 Journal of Medical Research
基金 国家自然科学基金资助项目(81102218)
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