摘要
目的探讨鼻内镜辅助手术治疗上颌窦癌的疗效及可行性分析。方法回顾分析近年来本院手术治疗的35例上颌窦癌患者的临床资料,将患者分为常规综合组和鼻内镜综合组。常规综合组采取传统手术方式治疗,鼻内镜综合组采用鼻内镜辅助手术治疗,两组术后均接受6MV-X线放射治疗(60～70)Gy/(30～35)F/(6～7)W。观察两组患者手术临床疗效,并进行鼻内镜辅助手术可行性分析。结果鼻内镜综合组3、5年生存率分别为70.6%(12/17)、56.3%(9/16),优于常规综合组的52.9%(9/17)、37.5%(6/16),差异有统计学意义(P<0.05)。鼻内镜综合组Ⅱ、Ⅲ、Ⅳ期患者5年生存率分别为100.0%、50.0%、25.0%,高于常规综合组的60.0%、42.9%、0.0%;本组Ⅳ期患者5年生存率远小于Ⅱ、Ⅲ期患者;差异均有统计学意义(P<0.05)。结论鼻内镜辅助手术可以彻底切除上颌窦癌,具有创伤小和避免面容损毁的特点,相比传统手术疗效和预后均有明显提高,并能提高患者生存质量。
Objective To explore the clinical effect of nasal endoscopy assisting operation to treat carcinoma of maxillary sinus and analyze the feasibility. Methods The clinical data of 35 patients with carcinoma of maxillary sinus treated in our hospital in recent few years. Divided the patients into the conventional comprehensive group and the nasal endoscopic comprehensive group. The conventional comprehensive group were treated with traditional operation, and the nasal endoscopic comprehensive group were treated with nasal endoscopy assisting operation. Two groups all received 6MV-X-ray radiotherapy （60-70） Gy/（30-35） F/（6-7） W after the operation. The clinical effect of operation of two groups were observed and the feasibility of nasal endoscopy assisting operation was analyzed. Results The survival rate of 3 and 5 years of the nasal endoscopic comprehensive group was respectively 70.6% （12/17） and 56.3% （9/16）, which was better than that of the conventional comprehensive group, that was 52.9% （9/17） and 37.5% （6/16）, which had statistical significance （P0.05）. The 5 years survival rate of stage Ⅱ, Ⅲ and Ⅳ in the nasal endoscopic comprehensive group was 100.0%, 50.0% and 25.0%, which was higher than that of the conventional comprehensive group, that was 60.0%, 42.9% and 0.0%, and the 5 years survival rate of stage Ⅳ was less than that of stage Ⅱ and Ⅲ in the conventional comprehensive group. The difference above all had statistical significance （P 0.05）. Conclusion Nasal endoscopy assisted surgery can complete resection of maxillary sinus carcinoma, with little injury and avoid face damaged characteristics, compare with the traditional surgical curative effect and prognosis are significantly improved, and it can improve the quality of life.
出处
《中国当代医药》
2012年第34期42-43,45,共3页
China Modern Medicine
关键词
鼻内镜手术
上颌窦癌
术后放疗
临床疗效
Nasal endoscopic operation
Carcinoma of maxillary sinus
Postoperation radiotherapy
Clinical efficacy
