摘要
目的:分析鼻内镜辅助下开放径路联合放疗治疗中晚期上颌窦恶性肿瘤患者的临床疗效,并探讨进一步提高疗效的方法。方法:回顾性分析29例鼻内镜辅助下开放径路联合放疗治疗中晚期上颌窦恶性肿瘤患者的生存情况。结果:29例患者癌肿病灶均顺利切除,其中7例Ⅳ期行术前放疗加手术加术后放疗,22例采用手术加术后放疗。中位随访时间60个月(23~129个月)。全组患者3年和5年存活率分别为72%、61%,其中Ⅱ期分别为90%、80%,Ⅲ+Ⅳ期分别为63%、51%。结论:鼻内镜辅助下开放径路联合放疗是治疗上颌窦恶性肿瘤的一种有效的综合治疗方法,无远处转移Ⅳ期患者联合术前放疗仍可获得很好疗效。
Objective：The aim of this study is to analyze the clinical effect of endoscopic assisted open pathway combined with radiotherapy in the treatment of patients with advanced maxillary sinus malignant tumor.Method：A retrospective analysis was performed on the survival of 29 patients with advanced maxillary sinus malignant tumor treated by endoscopic assisted open approach combined with radiotherapy.Result：A total of twenty-nine patients with cancer lesions were successfully resected,of which 7cases underwent preoperative radiotherapy plus surgery plus postoperative radiotherapy,22 cases were treated by surgery plus radiotherapy after operation.The median follow up time was 60months（23-129months）.The 3-year and 5-year survival rate of the patients was 72% and61%,respectively（90%and 80% was inⅡstage respectively.63%and 51% was inⅢ＋Ⅳstage respectively）.Conclusion：Endoscopic assisted open pathway combined with radiotherapy is an effective method for the treatment of maxillary sinus carcinoma,and it can still be well treated with preoperative radiotherapy in patients with stage IV without distant metastasis.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2017年第14期1078-1081,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
安徽省自然科学基金项目(No:1608085MH236)
蚌埠医学院第一附属医院高新技术项目(No:2017149)
关键词
上颌窦癌
鼻内镜
手术
综合治疗
生存率
maxillary sinus malignant tumor
nasal endoscopy
surgery
combined therapy
survival rate
