摘要
本文检测老年冠心病患者的血浆凝血酶 -抗凝血酶 复合物 (TAT)、血管性血友病因子抗原 (v WF:Ag)、蛋白 C抗原 (PC:Ag)、蛋白 S抗原 (PS:Ag)、P-选择素 (P- Selectin)、组织纤溶酶原激活物活性 (t- PA:A)、纤溶酶原激活剂抑制剂活性 (PAI:A )及 D-二聚体 (D- D) ,并与对照组比较。老年冠心组的 TAT、v WF:Ag、P- Selectin、PS:Ag、t- PA:A、PAI:A、D- D显著升高 (P<0 .0 5 )。其中 ,不稳定型心绞痛的 TAT、t- PA:A、PAI:A、D- D升高更明显 ,并与稳定型心绞痛有显著差异。结果表明 :老年冠心病患者主要表现为凝血系统激活、血管内皮损伤。
A series of hemostatic parameters which included thrombin antithrombin [HT5”,5SS]Ⅲ(complex) (TAT)、antigen level of von Willebrand Factor (vWF:Ag)、P Selectin、protein C and protein S antigen (PC:Ag、PS:Ag)、tissue plasminogen activator (t PA:A)、plasminogen activator inhibitor activity (PAI:A) and D dimer (D D) were measured in old people with CHD and normal controls. The levels of TAT, vWF:Ag, P Selectin, PS:Ag, PAI:A, D D were significantly increased (P<0 05) in CHD. The results showed the increase of coagulability, the injury of vascular endothelium, the activation of platelets and secondary hyperfibrinolysis in old people with CHD.
出处
《上海医学检验杂志》
2000年第2期81-82,84,共3页
Shanghai Journal of Medical Laboratory Sciences
关键词
冠心病
止血
凝血
纤维蛋白溶解系统
老年人
Coronary heart disease Hemostasis and Coagulation Fibrinolysis system
