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结直肠癌与免疫 被引量:1

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摘要 结直肠癌(colorectalcancer,CRC)是常见的消化道恶性肿瘤,尽管以分期为指导、手术治疗为核心的多学科综合治疗手段不断提高,但其预后仍不良,且患者就诊时大多已处于进展期,手术效果欠佳,术后常常很快发生复发和转移,放疗和化疗的严重副反应限制了其应用。研究发现,大多数实体肿瘤可诱导宿主的免疫反应,从而在肿瘤累及的组织局部形成免疫微环境,其中包括淋巴细胞、巨噬细胞、自然杀伤细胞(naturalkiller,NK)等,发挥抗肿瘤效应。
作者 王斌 方兰
出处 《医学新知》 CAS 2012年第5期324-327,共4页 New Medicine
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