摘要
微小RNA是一类长约22~25核苷酸的非编码RNA,在心肌细胞增殖凋亡以及疾病发病机制中发挥重要作用。近期关于微小RNA在心血管疾病中应用研究备受关注。在此,对微小RNA的特性与检测技术及在常见心血管疾病中应用价值进行阐述。
MicroRNA (miRNA), a type of 22-25nt non-coding RNA, plays an important role in proliferation and apoptosis of the eardiomyocyte , as well as the pathogenesis of some common cardiovascular diseases. Recently, researches on circulating miRNA in cardiovascular disease draw more attentions. This review will focus on the application value of miRNA in cardiovascular disease, the characteristics of miRNA and its detection technology will be described as well.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2012年第10期884-889,共6页
Chinese Journal of Laboratory Medicine
基金
天津市自然科学基金面上项目(12JCYBJC17400)
滨海新区医药卫生科技重点项目(2011BHKZ003)
关键词
心血管疾病
微RNAS
Cardiovascular diseases
Micro RNAs