摘要
目的 观察前列地尔注射液联合通心络胶囊对不稳定型心绞痛（UAP）患者血清白细胞介素6（IL-6）及高敏C反应蛋白（hs-CRP）的影响.方法 选择132例因UAP在我院住院治疗的患者,入院后均抽血检测IL-6及hs-CRP.采用完全随机的方法从中选取68例为对照组,给予基础抗心绞痛药物治疗,余64例作为观察组在基础治疗的基础上加用前列地尔及通心络.14 d后,对比分析两组的临床疗效及两项指标的变化.结果 治疗后观察组总有效率为89.1%,高于对照组的70.6%（P＜0.05）;两组IL-6及hs-CRP较治疗前均有明显降低（P＜0.01）,而观察组两项指标较对照组低（P＜0.05）.结论 IL-6及hs-CRP可反映UAP的严重程度.在基础抗心绞痛药物治疗UAP的基础上加用前列地尔注射液及通心络胶囊,能显著提高临床疗效.
Objective To observe the effect of alprostadil injection and tongxinluo capsule on serum IL-6 and hs-CRP in patients with UAP. Methods 132 patients of UAP were enrolled, all patients were taken blood testing of serum IL-6 and hs-CRP, in which 68 patients were randomly selected as the control group. All were given the basis of anti-angina drugs, the rest of 64 patients as the observation group, were accept alprostadil in- jection and tongxinluo capsule beside the basis of anti-angina drugs. The clinical efficacy and the two indicators 14 days later were compared. Results The total effective rate of the observation group was 89.1%, which was higher than the control group 70.6% （P〈0.05）, both IL-6 and hs-CRP were lower than before （P〈0.01）, the two indi-cators in observation group were lower than the control group （P〈0.05）. Condusion IL-6 and hs-CRP could re-flect the severity of the UAP, on the basis of anti-angina medication plus alprostadil injection and tongxinluo cap-sule could significantly improve the clinical efficacy.
出处
《中国心血管病研究》
CAS
2012年第9期655-657,共3页
Chinese Journal of Cardiovascular Research
